One of the most common health complaints in the community is headache. Headache affects people of all ages, races and socioeconomic levels. It is more common in women than in men. Some headaches can make people exhausted and have a negative impact on quality of life. There are many drugs to try in the treatment of headaches. The goal of migraine treatment is to reduce the triggering factors, to suppress the sensitivity of the nervous system and the events occurring in the vascular and surrounding vessels during pain. Basic treatment is divided into preventive and attack treatment. The frequency of the patient’s pain is effective in the treatment decision.